Efficient solutions for nitrogen evaporators
What is sample evaporation or nitrogen evaporation?
In analytical and life sciences laboratories, sample evaporation is a key step in sample preparation prior to chromatographic analysis. The aim of nitrogen evaporation is to gently remove solvents or to concentrate samples in a controlled manner without affecting the analytes. Sample evaporation refers to the targeted removal of solvents to concentrate samples and is an indispensable part of many analytical workflows in research, routine analysis and quality assurance.
Nitrogen evaporators are frequently used for this purpose. Nitrogen blow-off evaporation is one of the most established and reliable evaporation techniques, particularly for sensitive samples or high sample throughput.Chromalytic nitrogen generators for sample concentration supply high-purity nitrogen and are compatible with nitrogen evaporators from leading manufacturers such as Biotage, Thermo Fisher Scientific, GERSTEL, Organomation and many others.
How does sample evaporation work with a nitrogen evaporator?
The principle of nitrogen evaporation is based on a controlled gas flow: a nitrogen evaporator feeds nitrogen through an adjustable flow regulator and an integrated heating element. The heated nitrogen emerges through fine needles positioned directly above the sample tubes or microtitre plates. The continuous gas flow blows across the surface of the solvent, causing it to evaporate quickly, evenly and particularly gently. This method of sample evaporation using nitrogen enables reproducible, gentle evaporation even with sensitive analytes and is ideal when a large number of samples need to be processed in parallel. A stable and reliable nitrogen supply is essential for the smooth operation of a nitrogen evaporator. Chromalytic nitrogen generators for sample concentration offer a high-performance and tried-and-tested solution for sample preparation in the laboratory.
How can a high nitrogen requirement during sample evaporation be reliably met?
Sample evaporation requires a very large quantity of nitrogen, particularly during continuous operation or when handling high sample throughput. Conventional gas cylinders quickly reach their logistical and economic limits in such situations. At a time of rising costs for bottled gases, Chromalytic nitrogen generators for sample concentration offer a cost-effective and environmentally friendly alternative. They ensure a continuous supply of on-site generated nitrogen at all times – ideal for the reliable operation of nitrogen evaporators.
Furthermore, this eliminates the need for:
- ordering and replacing gas cylinders
- Storage and safety costs
- downtime caused by empty cylinders
Examples of analyses using sample evaporation

Clinical & Bioanalysis:
- Hormones
- Vitamins

Forensics & Toxicology
- Blood
- Urine
- Saliva
- Hair

Drugs & Substances:
- Steroids
- THC
- Opioids

Doping Testing:
- Blood
- Urine

Environment & Factors:
- Drinking water
- Wastewater
- Groundwater
- Oil & Grease
- PFAS

Food:
- Pesticides
- Acrylamides
- Mycotoxin

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